These reactions have included cardiac arrest, seizure, status epilepticus, and respiratory failure. Instances of nausea, vomiting, tremor, irritability, or palpitation have also occurred. Co-administration of CIPRO with other drugs primarily metabolized by CYP1A2 results in increased plasma concentrations of these drugs and could lead to clinically significant adverse events of the co-administered drug. As with other drugs, some isolates of Pseudomonas aeruginosa may develop resistance fairly rapidly during treatment with ciprofloxacin. Culture and susceptibility testing performed periodically during therapy will provide information not only on the therapeutic effect of the antimicrobial agent but also on the possible emergence of bacterial resistance. CIPRO is indicated in eminem addiction adults and pediatric patients from birth to 17 years of age for inhalational anthrax (post-exposure) to reduce the incidence or progression of disease following exposure to aerosolized Bacillus anthracis.
Although similar serious adverse reactions have been reported in patients receiving theophylline alone, the possibility that these reactions may be potentiated by CIPRO cannot be eliminated. If concomitant use cannot be avoided, monitor serum levels of theophylline and adjust dosage as appropriate see DRUG INTERACTIONS. Serious and occasionally fatal hypersensitivity (anaphylactic) reactions, some following the first dose, have been reported in patients receiving fluoroquinolone therapy, including CIPRO. Some reactions were accompanied by cardiovascular collapse, loss of consciousness, tingling, pharyngeal or facial edema, dyspnea, urticaria, and itching. Only a few mary jane meaning drug patients had a history of hypersensitivity reactions.
These differences are not considered clinically significant see Use In Specific Populations. Although bile concentrations of ciprofloxacin are several fold higher than serum concentrations after oral dosing, only a small amount of the dose administered is recovered from what happens if i report a drug dealer the bile as unchanged drug. An additional 1% to 2% of the dose is recovered from the bile in the form of metabolites. Approximately 20% to 35% of an oral dose is recovered from the feces within 5 days after dosing. This may arise from either biliary clearance or transintestinal elimination. In the event of acute overdosage, reversible renal toxicity has been reported in some cases.
If you doctor tells you to to split the 250-mg or 500-mg tablet, it may be broken in half along the scored line. Swallow the extended-release tablets whole; do not split, crush, or chew them. If you cannot swallow tablets or extended-release tablets whole, tell your doctor. One type of ciprofloxacin cannot be substituted for another. Be sure that you receive only the type of ciprofloxacin that was prescribed by your doctor.
This article provides several useful tips on medication disposal. You can also ask your pharmacist for information about how to dispose of your medication. How long a medication remains good can depend on many factors, including how and where you store the medication.
Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment. Taking ciprofloxacin may worsen muscle weakness in people with myasthenia gravis (a disorder of the nervous system that causes muscle weakness) and cause severe difficulty breathing or death. If you have myasthenia gravis and your doctor tells you that you should take ciprofloxacin, call your doctor immediately if you experience muscle weakness or difficulty breathing during your treatment. Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Talk to your doctor about the risks of taking ciprofloxacin or giving ciprofloxacin to your child. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
In rare cases, ciprofloxacin may cause damage to your aorta, the main blood artery of the body. Get emergency medical help if you have severe and constant pain in your chest, stomach, or back. Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases.
Cipro (floxacin) is a medication that belongs to the drug class, quinolone antibiotics. Cipro is available as a generic drug and is prescribed to treat infections of the skin, lungs, airways, bones, joints, and urinary tract infections caused by susceptible bacteria. Other drugs may interact with ciprofloxacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Use ciprofloxacin for the full prescribed length of time, even if your symptoms quickly improve.
Each Cipro 1000 mg tablet contains 1000 mg of ciprofloxacin as ciprofloxacin HCl (574.9 mg, calculated as ciprofloxacin on the dried basis) and ciprofloxacin†(425.2 mg, calculated on the dried basis). The inactive ingredients are crospovidone, hypromellose, magnesium stearate, polyethylene glycol, silica colloidal anhydrous, succinic acid, and titanium dioxide. Talk to your care team regarding the use of this medication in children. A special MedGuide will be given to you by the pharmacist with each prescription and refill.
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